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The Women’s Health InitiativeWHIestrogen-alone substudy reported increased risks of stroke and deep vein thrombosisDVTin postmenopausal women with daily oral conjugated estrogensCEaloneThe WHI estrogen-plus-progestin substudy reported increased risks of DVTpulmonary embolismstrokeand myocardial infarction in postmenopausal women with daily oral CE combined with medroxyprogesterone acetateMPAIn the absence of comparable datathese risks should be assumed to be similar for other dosage forms of estrogens.
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1While you are using estrogensit is important to visit your doctor at least once a year for a check-up.
Most prospective studies of efficacy for this indication have been carried out in white menopausal womenwithout stratification by other risk factorsand tend to show a universally salutary effect on bone.
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read this patient information before you start using estrace vaginal cream and read what you get each time you refill your estrace vaginal cream prescrption.